Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131791 | 0.91 | KDM4E (0.62) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| Citric Acid SCHEMBL6131999 | 0.87 | MEN1 (0.53) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL514870 | 0.86 | KMT2A (0.82) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10390463 | 0.81 | KDM4E (0.80) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6131836 | 0.81 | HTR7 (0.50) | KDM4ECYP1A2CYP3A4CYP2D6BLM | |
| Citric Acid SCHEMBL6131788 | 0.80 | KDM4E (0.50) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6131979 | 0.79 | HTR7 (0.49) | KDM4ECYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL5070866 | 0.75 | CYP1A2 (0.69) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL29976523 | 0.75 | DRD2 (0.46) | KDM4ECYP1A2CYP3A4CYP2D6SIGMAR1 | |
| SCHEMBL19806083 | 0.75 | DRD2 (0.46) | KDM4ECYP1A2CYP3A4CYP2D6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |