Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26824 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ALMNATDP1 | |
| SCHEMBL27622479 | 0.80 | CYP2D6 (0.40) | ALDH1A1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL5147427 | 0.79 | USP2 (0.35) | ALDH1A1LMNA | |
| SCHEMBL6885636 | 0.79 | USP2 (0.35) | ALDH1A1LMNA | |
| SCHEMBL25013 | 0.78 | LMNA (0.41) | ALDH1A1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL27641459 | 0.77 | APOBEC3A (0.38) | ALDH1A1MAPTLMNAL3MBTL1POLB | |
| SCHEMBL5147250 | 0.77 | SMN1; SMN2 (0.33) | ALDH1A1MAPTLMNA | |
| SCHEMBL4337366 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ALMNATDP1 | |
| SCHEMBL5145781 | 0.74 | USP2 (0.32) | ALDH1A1LMNA | |
| SCHEMBL27641457 | 0.74 | ADRB2 (0.43) | ALDH1A1KMT2ALMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569895-A4 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1569895-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052844-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2004-06-24 | — | — | WO | disclosed |