Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148945 | 0.91 | RPA1 (0.53) | RPA1 | |
| SCHEMBL5148803 | 0.86 | RPA1 (0.52) | RPA1MALT1 | |
| SCHEMBL14504708 | 0.86 | — | — | |
| SCHEMBL5150683 | 0.85 | MALT1 (0.56) | RPA1MALT1 | |
| SCHEMBL5147830 | 0.84 | PTGS1 (0.51) | RPA1MALT1 | |
| SCHEMBL5148567 | 0.83 | PTGS2 (0.68) | — | |
| SCHEMBL5148771 | 0.83 | PTGS2 (0.62) | RPA1MALT1 | |
| SCHEMBL5171748 | 0.82 | PTGS2 (0.50) | — | |
| SCHEMBL9207296 | 0.82 | PTGS2 (0.59) | RPA1 | |
| SCHEMBL5152255 | 0.82 | RPA1 (0.49) | RPA1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-B1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | ASTELLAS PHARMA INC (JP) | 2011-12-21 | — | — | EP | disclosed |
| US-20070112037-A1 | Pyrazole Derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| US-7183306-B2 | Pyrazole derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112037-A1 | Pyrazole Derivatives | CYP11B2, CYP11B1, CYP3A43 | RPA1 2143/4885MALT1 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.