Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148889 | 0.91 | RPA1 (0.50) | RPA1 | |
| SCHEMBL5148853 | 0.84 | RPA1 (0.54) | RPA1 | |
| SCHEMBL5152432 | 0.83 | RPA1 (0.60) | RPA1 | |
| SCHEMBL9207296 | 0.83 | PTGS2 (0.59) | RPA1 | |
| SCHEMBL5147699 | 0.82 | PTGS2 (0.54) | RPA1 | |
| SCHEMBL5423109 | 0.82 | RPA1 (0.59) | RPA1 | |
| SCHEMBL5148639 | 0.82 | RPA1 (0.58) | RPA1 | |
| SCHEMBL14504421 | 0.81 | PTGS1 (0.48) | — | |
| SCHEMBL5171748 | 0.81 | PTGS2 (0.50) | — | |
| SCHEMBL5427928 | 0.81 | ALOX5 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-B1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | ASTELLAS PHARMA INC (JP) | 2011-12-21 | — | — | EP | disclosed |
| US-7183306-B2 | Pyrazole derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-27 | — | — | US | disclosed |