Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17966634 | 0.78 | KDM4E (0.45) | ALDH1A1CYP11B1CYP11B2KDM4EGRM5 | |
| SCHEMBL16045938 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTNOTUMKDM4E | |
| SCHEMBL28050493 | 0.77 | KMT2A (0.49) | ALDH1A1LMNAMAPTNOTUMKDM4E | |
| SCHEMBL12438818 | 0.77 | HTT (0.46) | ALDH1A1LMNASMN1; SMN2NOTUMKDM4E | |
| SCHEMBL15935401 | 0.77 | HTT (0.51) | ALDH1A1LMNAMAPTSMN1; SMN2CYP11B1 | |
| SCHEMBL1060286 | 0.77 | P2RX7 (0.56) | ALDH1A1LMNAMAPTSMN1; SMN2ELOVL1 | |
| SCHEMBL23036953 | 0.75 | MTOR (0.52) | ALDH1A1SMN1; SMN2ELOVL1EP300KDM4E | |
| SCHEMBL15352616 | 0.74 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2NOTUM | |
| SCHEMBL2584832 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2NOTUM | |
| SCHEMBL15824279 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |