Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036953 | 0.82 | MTOR (0.52) | P2RX7CYP2C9HTTHSD17B10L3MBTL1 | |
| SCHEMBL12438818 | 0.81 | HTT (0.46) | P2RX7HTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16045938 | 0.81 | ALDH1A1 (0.44) | P2RX7PTGS2MAPTHTTHSD17B10 | |
| SCHEMBL23036951 | 0.80 | MTOR (0.54) | P2RX7CYP2C9MAPTHTTHSD17B10 | |
| SCHEMBL30970914 | 0.80 | MTOR (0.54) | P2RX7CYP2C9MAPTHTTHSD17B10 | |
| SCHEMBL20422254 | 0.80 | HTT (0.45) | P2RX7CYP2C9MAPTHTTTSHR | |
| SCHEMBL9978532 | 0.79 | ALDH1A1 (0.50) | P2RX7CYP2C9ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4251316 | 0.79 | MEN1 (0.54) | P2RX7MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL17261501 | 0.77 | NPC1 (0.53) | CYP2C9MAPTHTTTSHRHSD17B10 | |
| SCHEMBL17261502 | 0.77 | NPC1 (0.53) | CYP2C9MAPTHTTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | claimed |
| US-11597728-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-07 | — | — | US | claimed |
| EP-3856179-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2021-08-04 | — | — | EP | claimed |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | claimed |
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | claimed |
| US-12600717-B2 | Tricyclic compounds as inhibitors of KRAS | INCYTE CORPORATION (US) | 2026-04-14 | — | — | US | disclosed |
| US-20240327410-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-03 | — | — | US | disclosed |
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-112368279-B | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2024-05-28 | — | — | CN | disclosed |
| US-11993601-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV | 2024-05-28 | — | — | US | disclosed |
| EP-4370515-A1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS | Incyte Corporation (US) | 2024-05-22 | — | — | EP | disclosed |
| CN-111892601-B | Pyridopyrazolocinnoline compound and preparation method and application thereof | 陕西大美化工科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| EP-1594438-A2 | USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES | L'OREAL (FR) | 2005-11-16 | — | — | EP | disclosed |
| EP-1565150-A1 | COMPOSITION FOR HAIR CARE OR EYELASHES CONTAINING A PYRAZOL-CARBOXAMIDE, ITS USE FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR PREVENTING LOSS THEREOF | L'OREAL (FR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| US-20040235831-A1 | Composition for caring for the hair or the eyelashes, containing a pyrazolecarboxamide compound, use thereof for stimulating the growth of the hair and the eyelashes and/or for reducing their loss | SOCIETE L'OREAL, S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| WO-2004073594-A2 | USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES | L'OREAL (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004047776-A1 | COMPOSITION FOR HAIR CARE OR EYELASHES CONTAINING A PYRAZOL-CARBOXAMIDE, ITS USE FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR PREVENTING LOSS THEREOF | L'OREAL (FR) | 2004-06-10 | — | — | WO | disclosed |
| CN-1289326-A | N-[(substituted five-membered di-or thiaza diunsaturated ring) carbonyl] guanidine derivatives for the treatment of ischemia | PFIZER PROD INC (US) | 2001-03-28 | — | — | CN | disclosed |
| CN-1153779-A | 2-(4-pyrazoloxy-pyrimidin-5-yl) acetic acid derivatives | SANDOZ LTD (CH) | 1997-07-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600717-B2 | Tricyclic compounds as inhibitors of KRAS | KRAS, NRAS, HRAS | P2RX7 4046/4885CYP2C9 2480/4885PTGS2 4449/4885 |
| US-11993601-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | P2RX7 1597/4885CYP2C9 773/4885PTGS2 984/4885 |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | P2RX7 1597/4885CYP2C9 773/4885PTGS2 984/4885 |
| US-11597728-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | P2RX7 1597/4885CYP2C9 773/4885PTGS2 984/4885 |
| US-20240327410-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | P2RX7 1597/4885CYP2C9 773/4885PTGS2 984/4885 |
| US-20040235831-A1 | Composition for caring for the hair or the eyelashes, containing a pyrazolecarboxamide compound, use thereof for stimulating the growth of the hair and the eyelashes and/or for reducing their loss | BCOR, HCRTR1, RCOR1 | P2RX7 2136/4885CYP2C9 2023/4885PTGS2 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.