Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217415 | 0.84 | NQO2 (0.56) | NQO2MTNR1ACA12CA4CA7 | |
| SCHEMBL13533413 | 0.72 | NQO2 (0.50) | NQO2MTNR1AMAPTHTTALDH1A1 | |
| SCHEMBL8414964 | 0.72 | MAPT (0.47) | MAPTHTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL19122441 | 0.71 | MAPT (0.43) | MAPTHTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL8858591 | 0.71 | NQO2 (0.58) | NQO2MTNR1ACA12CA4CA9 | |
| SCHEMBL30420224 | 0.71 | MTNR1A (0.54) | NQO2MTNR1AMAPTHTTALDH1A1 | |
| SCHEMBL28519744 | 0.70 | MEN1 (0.63) | NQO2MTNR1AALDH1A1HSD17B10KDM4E | |
| Ammonia Solution, Strong SCHEMBL9730743 | 0.70 | MAPT (0.42) | MAPTHTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL606293 | 0.70 | MTNR1A (0.63) | NQO2MTNR1AHTTALDH1A1KDM4E | |
| SCHEMBL8794788 | 0.69 | HPGD (0.64) | NQO2MTNR1ACA12CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664013-A4 | CALCILYTIC COMPOUNDS | GLAXO GROUP LTD (GB) | 2007-03-14 | — | — | EP | disclosed |
| EP-1664013-A1 | CALCILYTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005030749-A1 | CALCILYTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-04-07 | — | — | WO | disclosed |