Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134616 | 0.89 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AMAPTTDP1GAA | |
| SCHEMBL9609808 | 0.89 | SMN1; SMN2 (0.82) | SMN1; SMN2RAB9AMAPTGAAGFER | |
| SCHEMBL7251623 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9AMAPTGAAGFER | |
| SCHEMBL515017 | 0.81 | MAPT (0.59) | SMN1; SMN2RAB9AMAPTTDP1GAA | |
| SCHEMBL854996 | 0.80 | RAB9A (0.61) | SMN1; SMN2RAB9AMAPTTDP1GAA | |
| SCHEMBL514410 | 0.80 | MAPT (0.53) | SMN1; SMN2RAB9AMAPTTDP1GAA | |
| SCHEMBL13513998 | 0.80 | RAB9A (0.67) | SMN1; SMN2RAB9AMAPTTDP1GAA | |
| SCHEMBL78108 | 0.80 | MAPT (0.53) | RAB9AMAPTTDP1GAAGFER | |
| SCHEMBL18814226 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AMAPTTDP1KDM4E | |
| SCHEMBL17518815 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9AMAPTGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287498-B | Psma antibody-drug conjugates | PSMA DEV COMPANY LLC | 2013-03-27 | — | — | CN | claimed |
| CN-101287498-A | PSMA antibody-drug conjugates | PSMA DEV COMPANY LLC (US) | 2008-10-15 | — | — | CN | claimed |
| EP-4522618-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | Merck Patent GmbH (DE) | 2025-03-19 | — | — | EP | disclosed |
| CN-116348109-B | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| WO-2023220541-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | MERCK PATENT GMBH (DE) | 2023-11-16 | — | — | WO | disclosed |
| US-20040053156-A1 | Photosensitive resin precursor composition | TORAY INDUSTRIES, INC. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6696112-B2 | POSITIVE-TYPE, PHOTOSENSITIVITY; FLAT PANEL DISPLAYS | TORAY INDUSTRIES, INC. (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-1388758-A1 | Photosensitive heat resistant resin precursor composition | TORAY INDUSTRIES, INC. (JP) | 2004-02-11 | — | — | EP | disclosed |
| EP-1296540-A1 | DISPLAY | TORAY INDUSTRIES, INC. (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-20020162998-A1 | Display | TORAY INDUSTRIES, INC. (JP) | 2002-11-07 | — | — | US | disclosed |
| EP-0878740-A1 | Radiation sensitive polymer composition | TORAY INDUSTRIES, INC. (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0018939-B1 | 1:2 METAL COMPLEX DYESTUFFS OF AZOMETHINES, PROCESS FOR THEIR PREPARATION AND PROCESS FOR DYEING AND PRINTING BY USING THESE DYESTUFFS | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| US-4315854-A | Chromium and cobalt complex amino hydroxy azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0018939-A1 | 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs | CIBA-GEIGY AG (CH) | 1980-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | PDXK, DTYMK, HIPK1 | SMN1; SMN2 3927/4885RAB9A 2076/4885MAPT 3283/4885 |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | F7, F11, HABP2 | SMN1; SMN2 4054/4885RAB9A 3518/4885MAPT 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.