SCHEMBL51507

SCHEMBL51507

O=C(c1ccccc1)c1cc2ccccc2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.73
ALDH1A1 P00352 5/20 0.73
MAOA P21397 4/20 0.73
MIF P14174 2/20 0.73
HPGD P15428 2/20 0.73
CA12 O43570 2/20 0.73
CA9 Q16790 2/20 0.73
TSHR P16473 2/20 0.73
CA1 P00915 1/20 0.73
CA3 P07451 1/20 0.73
CA4 P22748 1/20 0.73
CA6 P23280 1/20 0.73
CA5A P35218 1/20 0.73
CA7 P43166 1/20 0.73
GPR35 Q9HC97 1/20 0.73
CA14 Q9ULX7 1/20 0.73
CA5B Q9Y2D0 1/20 0.73
RAB9A P51151 4/20 0.68
NPC1 O15118 3/20 0.68
KDM4E B2RXH2 4/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5562065 0.95 MAOB (0.68) MAOBALDH1A1MAOAMIFHPGD
SCHEMBL5996884 0.94 MAOB (0.66) MAOBALDH1A1MAOAMIFHPGD
Coumarin SCHEMBL194933 0.91 ALDH1A1 (0.67) MAOBALDH1A1MAOAMIFHPGD
SCHEMBL29539474 0.90 MAOB (0.77) MAOBALDH1A1MAOAHPGDCA12
SCHEMBL279860 0.90 MAOB (0.77) MAOBALDH1A1MAOAHPGDCA12
SCHEMBL6881825 0.89 MAOB (0.72) MAOBALDH1A1MAOAMIFHPGD
SCHEMBL11097358 0.88 MAOB (0.60) MAOBALDH1A1MAOAMIFHPGD
SCHEMBL28014855 0.88 ALDH1A1 (0.67) MAOBALDH1A1MAOAMIFHPGD
SCHEMBL6832346 0.86 MAOB (0.76) MAOBALDH1A1MAOAMIFHPGD
SCHEMBL18188888 0.86 MAOB (0.62) MAOBALDH1A1MAOAMIFHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN claimed
CN-106008434-B A kind of synthetic method of 3- benzoyls coumarin kind compound 青岛农业大学 2018-06-26 CN claimed
US-9834740-B2 Photoactivators THE PROCTER & GAMBLE COMPANY (US) 2017-12-05 US claimed
EP-3097168-A1 SYSTEMS AND METHODS FOR TREATING A SURFACE The Procter & Gamble Company (US) 2016-11-30 EP claimed
EP-3097176-A1 PHOTOACTIVATORS The Procter & Gamble Company (US) 2016-11-30 EP claimed
EP-3097169-A1 CONSUMER PRODUCT COMPOSITIONS The Procter & Gamble Company (US) 2016-11-30 EP claimed
CN-106008434-A Synthetic method for 3-benzoyl coumarin compound 青岛农业大学 2016-10-12 CN claimed
CN-105934510-A Photoactivators 宝洁公司 2016-09-07 CN claimed
US-20150210963-A1 Systems and Methods for Treating a Surface THE PROCTER & GAMBLE COMPANY 2015-07-30 US claimed
US-20150210960-A1 Photoactivators THE PROCTER & GAMBLE COMPANY 2015-07-30 US claimed
US-20150210964-A1 Consumer Product Compositions THE PROCTER & GAMBLE COMPANY 2015-07-30 US claimed
WO-2015112675-A1 PHOTOACTIVATORS THE PROCTER & GAMBLE COMPANY (US) 2015-07-30 WO claimed
WO-2015112667-A1 SYSTEMS AND METHODS FOR TREATING A SURFACE THE PROCTER & GAMBLE COMPANY (US) 2015-07-30 WO claimed
EP-0298030-B1 PROCESS FOR FORMING IMAGES CIBA-GEIGY AG (CH) 1992-10-28 EP claimed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US claimed
US-4978604-A Process for forming images CIBA-GEIGY CORPORATION (US) 1990-12-18 US claimed
EP-0298030-A2 Process for forming images CIBA-GEIGY AG (CH) 1989-01-04 EP claimed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210960-A1 Photoactivators NQO1, TYR, CYP1A1 MAOB 416/4885ALDH1A1 78/4885MAOA 147/4885
US-20150210963-A1 Systems and Methods for Treating a Surface HMBS, PPOX, TTPA MAOB 62/4885ALDH1A1 1283/4885MAOA 29/4885
US-20150210964-A1 Consumer Product Compositions NQO1, TYR, ETFA MAOB 13/4885ALDH1A1 27/4885MAOA 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.