Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226915 | 0.88 | RAB9A (0.50) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL5071427 | 0.80 | DGAT1 (0.44) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL13752563 | 0.72 | NPC1 (0.54) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL5067991 | 0.71 | RAB9A (0.50) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL6032026 | 0.70 | SMN1; SMN2 (0.39) | KMT2ANPC1RAB9AMEN1DGAT1 | |
| SCHEMBL3100283 | 0.69 | RAB9A (0.56) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL12265910 | 0.69 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13752572 | 0.68 | RAB9A (0.58) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL13752570 | 0.67 | PSEN1 (0.58) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL1748034 | 0.67 | SMN1; SMN2 (0.44) | RAB9AALDH1A1SMN1; SMN2MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874317-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Pharmaceuticals Corporation (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006113919-A2 | ARYL ALKYL ACID DERIVATIVES FOR AND USE THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |