SCHEMBL5151208

SCHEMBL5151208

S=c1[nH]ncn1Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
DBH P09172 1/20 0.51
KDM4E B2RXH2 3/20 0.47
POLB P06746 1/20 0.47
GAA P10253 3/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
LMNA P02545 1/20 0.44
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
TNF P01375 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
IDO1 P14902 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8489645 0.78 HPGD (0.46) ALDH1A1KDM4EGAAHPGDLMNA
SCHEMBL6261531 0.75 TNF (0.49) ALDH1A1DBHKDM4EPOLBGAA
SCHEMBL2034751 0.68 KDM4E (0.49) ALDH1A1DBHKDM4EPOLBGAA
SCHEMBL11079680 0.68 DBH (1.00) ALDH1A1DBHPOLBHPGDCYP1A2
SCHEMBL6541971 0.67 TDP1 (0.62) ALDH1A1HPGDLMNAALOX15
SCHEMBL22206418 0.66 NPC1 (0.51) ALDH1A1KDM4EHPGDCYP1A2CYP2C19
SCHEMBL4736170 0.64 KMT2A (0.58) ALDH1A1DBHKDM4EGAAHPGD
SCHEMBL22206420 0.64 PKM (0.44) ALDH1A1KDM4EGAALMNACYP11B1
SCHEMBL2284397 0.64 DBH (0.57) ALDH1A1DBHKDM4EHPGDCYP3A4
SCHEMBL11154684 0.64 ALDH1A1 (0.57) ALDH1A1DBHKDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831762-A1 BLOCKED ALIPHATIC THIOL STABILIZERS FOR PHOTOTHERMOGRAPHIC MATERIALS Carestream Health, Inc. (US) 2007-09-12 EP disclosed
EP-1735661-B1 THERMALLY DEVELOPABLE MATERIALS CONTAINING ORGANIC SILVER SALTS EASTMAN KODAK CO (US) 2007-09-05 EP disclosed
US-7169543-B2 Blocked aliphatic thiol stabilizers for photothermographic materials EASTMAN KODAK COMPANY (US) 2007-01-30 US disclosed
US-7169544-B2 Thermally developable materials containing thermal solvents EASTMAN KODAK COMPANY (US) 2007-01-30 US disclosed
US-7166421-B2 Aqueous-based photothermographic materials containing tetrafluoroborate salts EASTMAN KODAK COMPANY (US) 2007-01-23 US disclosed
US-7153635-B1 Thermally developable materials processable at lower temperatures EASTMAN KODAK COMPANY (US) 2006-12-26 US disclosed
US-7132228-B2 Developer dispersions for thermally developable materials EASTMAN KODAK COMPANY (US) 2006-11-07 US disclosed
US-20060240366-A1 THERMALLY DEVELOPABLE MATERIALS CONTAINING THERMAL SOLVENTS EASTMAN KODAK COMPANY 2006-10-26 US disclosed
US-7097963-B1 Halogen substituted tetraazaindene compounds in photothermographic materials EASTMAN KODAK COMPANY (US) 2006-08-29 US disclosed
US-7074549-B2 Photothermographic materials containing phosphors and methods of using same EASTMAN KODAK COMPANY (US) 2006-07-11 US disclosed
US-20050233269-A1 Photothermographic materials containing phosphors and methods of using same EASTMAN KODAK COMPANY 2005-10-20 US disclosed
WO-2005073803-A1 THERMALLY DEVELOPABLE COMPOSITIONS AND IMAGING MATERIALS EASTMAN KODAK COMPANY (US) 2005-08-11 WO disclosed
US-20050164136-A1 Ascorbic acid compounds as reducing agents for thermally developable compositions and imaging materials EASTMAN KODAK COMPANY 2005-07-28 US disclosed
WO-2005050311-A1 STABILIZED HIGH-SPEED EMULSIONS AND PHOTOTHERMOGRAPHIC MATERIALS EASTMAN KODAK COMPANY (US) 2005-06-02 WO disclosed
US-20050106514-A1 Stabilized high-speed thermally developable emulsions and photothermographic materials EASTMAN KODAK COMPANY 2005-05-19 US disclosed
US-6770428-B2 Photothermographic materials containing high iodide core-shell emulsions EASTMAN KODAK COMPANY 2004-08-03 US disclosed
US-20040096784-A1 PHOTOTHERMOGRAPHIC MATERIALS CONTAINING HIGH IODIDE CORE-SHELL EMULSIONS EASTMAN KODAK COMPANY 2004-05-20 US disclosed
EP-1420291-A1 Photothermographic materials containing high iodide core-shell emulsions EASTMAN KODAK COMPANY (US) 2004-05-19 EP disclosed
EP-1400844-A2 Photothermographic materials containing high iodide emulsions EASTMAN KODAK COMPANY (US) 2004-03-24 EP disclosed
US-20040053173-A1 Photothermographic materials containing high iodide emulsions EASTMAN KODAK COMPANY 2004-03-18 US disclosed