Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 9/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | MMP9 | P14780 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392048 | 0.93 | MMP13 (0.50) | KMT2AMMP13ESR1ESR2MAPK1 | |
| SCHEMBL9874462 | 0.90 | MMP13 (0.50) | KMT2AMMP13ESR1ESR2ALDH1A1 | |
| SCHEMBL8722675 | 0.90 | ESR1 (0.44) | KMT2AMMP13ESR1ESR2MAPK1 | |
| SCHEMBL10391857 | 0.87 | ESR1 (0.41) | KMT2AMMP13ESR1MAPK1ALDH1A1 | |
| SCHEMBL8722684 | 0.87 | ESR1 (0.47) | KMT2AMMP13ESR1ESR2MAPK1 | |
| SCHEMBL9773502 | 0.85 | MMP13 (0.38) | KMT2AMMP13MAPK1ALDH1A1KDM4E | |
| SCHEMBL10401778 | 0.81 | DDB1 (0.44) | KMT2AMMP13MAPK1NPSR1TDP1 | |
| SCHEMBL9730839 | 0.81 | MMP13 (0.52) | KMT2AMMP13MGLLTDP1ALDH1A1 | |
| SCHEMBL9773395 | 0.80 | MMP13 (0.43) | MMP13ALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL9736118 | 0.80 | CA12 (0.56) | KMT2AMMP13NPSR1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028180-A1 | SPIRODILACTAM POLYCARBONATE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2012-02-02 | — | — | US | claimed |
| EP-0372656-B1 | Polymers comprising spirolactam units | SHELL INT RESEARCH (NL) | 1995-06-07 | — | — | EP | claimed |
| US-5061780-A | Poly(ether-bis-imide-spiro dilactam) polymer | SHELL OIL COMPANY (US) | 1991-10-29 | — | — | US | claimed |
| US-4939251-A | Novel spirolactones | SHELL OIL COMPANY (US) | 1990-07-03 | — | — | US | claimed |
| EP-0372656-A2 | Polymers comprising spirolactam units | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-13 | — | — | EP | claimed |
| US-4889907-A | Polymeric polyhyroxy polyether containing 1,6-diazaspiro-[4.4]nonane-2,7-dione units | SHELL OIL COMPANY (US) | 1989-12-26 | — | — | US | claimed |
| US-4847388-A | Polycyclic unsaturated ethers and esters | SHELL OIL COMPANY (US) | 1989-07-11 | — | — | US | claimed |
| US-8361624-B2 | Spirodilactam polycarbonate intermediate transfer members | XEROX CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120301725-A1 | SPIRODILACTAM POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS | XEROX CORPORATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-8304152-B2 | Spirodilactam polycarbonate containing photoconductors | XEROX CORPORATION (US) | 2012-11-06 | — | — | US | disclosed |
| US-20120028180-A1 | SPIRODILACTAM POLYCARBONATE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2012-02-02 | — | — | US | disclosed |
| US-8071710-B2 | Thermoplastic polyphenoxyquinoxaline and method of preparing the same | THE UNIVERSITY OF AKRON (US) | 2011-12-06 | — | — | US | disclosed |
| EP-0443688-B1 | Spirodilactam-arylsulfone oligomers | SHELL INT RESEARCH (NL) | 1998-05-06 | — | — | EP | disclosed |
| US-4906725-A | Polycarbonate containing spiro dilactam segment | SHELL OIL COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4895942-A | Novel epoxy compounds | SHELL OIL COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4889907-A | Polymeric polyhyroxy polyether containing 1,6-diazaspiro-[4.4]nonane-2,7-dione units | SHELL OIL COMPANY (US) | 1989-12-26 | — | — | US | disclosed |
| US-4888408-A | Polymeric polyhydroxy polyether containing 1,6-diazaspiro-[4.4]nonane-2,7-dione units | SHELL OIL COMPANY (US) | 1989-12-19 | — | — | US | disclosed |
| US-4886863-A | Novel alkenylphenol derivatives | SHELL OIL COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0336475-A1 | 1,6-diazaspiro (4,4)nonane-2,7-dione derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-10-11 | — | — | EP | disclosed |
| US-4847388-A | Polycyclic unsaturated ethers and esters | SHELL OIL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |