Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401778 | 0.81 | DDB1 (0.44) | MMP13MMP2MMP3MMP9MEN1 | |
| SCHEMBL515166 | 0.81 | KMT2A (0.48) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL9773395 | 0.80 | MMP13 (0.43) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730386 | 0.80 | MMP13 (0.59) | MMP13MMP2MMP3MMP9MEN1 | |
| SCHEMBL9730368 | 0.78 | MMP13 (0.63) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9383630 | 0.77 | MMP13 (0.39) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9736118 | 0.77 | CA12 (0.56) | MMP13MMP2MMP3MMP9MEN1 | |
| SCHEMBL9729436 | 0.76 | ALDH1A1 (0.36) | MMP13MMP2MMP3MMP9MEN1 | |
| SCHEMBL10392048 | 0.75 | MMP13 (0.50) | MMP13MMP2MMP3MMP9MEN1 | |
| SCHEMBL9644271 | 0.75 | MMP13 (0.38) | MMP13MMP2MMP3MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093499-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |