Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.50 |
| ▸ | MMP3 | P08254 | 5/20 | 0.50 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515166 | 0.90 | KMT2A (0.48) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL9874429 | 0.86 | MMP13 (0.52) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL9729935 | 0.86 | MMP13 (0.66) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9773502 | 0.85 | MMP13 (0.38) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL10392048 | 0.84 | MMP13 (0.50) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL8722675 | 0.81 | ESR1 (0.44) | MMP13KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL10391857 | 0.79 | ESR1 (0.41) | MMP13KMT2AMEN1ESR1ALDH1A1 | |
| SCHEMBL8722684 | 0.79 | ESR1 (0.47) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL10466906 | 0.76 | ALDH1A1 (0.45) | MMP13MMP2MMP3MMP9KMT2A | |
| SCHEMBL9734487 | 0.75 | ALDH1A1 (0.50) | MMP13MMP2MMP3MMP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001213-A | Thermosetting resin compositions | SHELL OIL COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| US-4939227-A | Novel thermoplastic polymers | SHELL OIL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4933423-A | Thermosetting resin compositions | SHELL OIL COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| US-4895942-A | Novel epoxy compounds | SHELL OIL COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4888408-A | Polymeric polyhydroxy polyether containing 1,6-diazaspiro-[4.4]nonane-2,7-dione units | SHELL OIL COMPANY (US) | 1989-12-19 | — | — | US | disclosed |