Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21701103 | 0.83 | GPR3 (0.33) | THRBMAPK1HTR2AHTR2CADRA2A | |
| SCHEMBL14364126 | 0.79 | TSHR (0.42) | MAPK1TSHRALDH1A1TP53 | |
| SCHEMBL29309181 | 0.77 | ALDH1A1 (0.41) | HTR2CHTR2BTSHRALDH1A1HTT | |
| SCHEMBL14364124 | 0.74 | ALDH1A1 (0.39) | HTR2AHTR2CALDH1A1MAOAMAOB | |
| SCHEMBL14364127 | 0.74 | HTT (0.35) | MAPK1HTR2CTSHRALDH1A1HTT | |
| SCHEMBL30861792 | 0.73 | HSP90AA1 (0.37) | HTR2AHTR2CHTR2BTSHRMAOA | |
| SCHEMBL4900253 | 0.73 | HSP90AA1 (0.37) | HTR2AHTR2CHTR2BTSHRMAOA | |
| SCHEMBL13302911 | 0.72 | POLB (0.45) | THRBMAPK1TSHRALDH1A1POLB | |
| SCHEMBL30408659 | 0.72 | POLB (0.45) | THRBMAPK1TSHRALDH1A1POLB | |
| SCHEMBL10616663 | 0.70 | MAPT (0.43) | THRBHTR2ATSHRALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1738646-B1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON INC (US) | 2013-03-20 | — | — | EP | disclosed |
| US-7291649-B2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291649-B2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. | 2007-01-04 | — | — | US | disclosed |
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. | 2007-01-04 | — | — | US | disclosed |
| EP-1738646-A2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ALPG, DDT, ACR | THRB 4406/4885MAPK1 4703/4885HTR2A 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.