Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5894508 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL18095030 | 0.66 | MAPT (0.38) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL6406728 | 0.64 | ALDH1A1 (0.54) | ALDH1A1MAPTGLAHPGDACHE | |
| Acridine SCHEMBL4906921 | 0.64 | ALDH1A1 (0.65) | ALDH1A1MAPTGLAHPGDACHE | |
| Acridine SCHEMBL11600717 | 0.63 | ALDH1A1 (0.71) | ALDH1A1MAPTGLAHPGDACHE | |
| Acridine SCHEMBL1051621 | 0.63 | ALDH1A1 (0.71) | ALDH1A1MAPTGLAHPGDACHE | |
| Acridine SCHEMBL10831095 | 0.63 | ALDH1A1 (0.71) | ALDH1A1MAPTGLAHPGDACHE | |
| Acridine SCHEMBL2140243 | 0.63 | ALDH1A1 (0.71) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL1515043 | 0.63 | ALDH1A1 (0.50) | ALDH1A1MAPTGLAHPGDACHE | |
| Hydrochloric Acid SCHEMBL8523156 | 0.62 | ALDH1A1 (0.48) | ALDH1A1MAPTGLAHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3391055-A1 | REACTIVE MAGNETIC EMULSIONS | Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (FR) | 2018-10-24 | — | — | EP | disclosed |
| CN-102753544-A | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties | UNIV MICHIGAN | 2012-10-24 | — | — | CN | disclosed |
| CN-102753179-A | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties | UNIV MICHIGAN | 2012-10-24 | — | — | CN | disclosed |
| CN-101321534-A | Benzodiazepines as HCV inhibitors | TIBOTEC PHARM LTD (IE) | 2008-12-10 | — | — | CN | disclosed |
| EP-1617807-A4 | SUBSTITUTED 1,4-DIAZEPINES AND USES THEREOF | ORTHO MCNEIL PHARM INC (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060235007-A1 | Substituted 1,4-diazepines and uses thereof | LU TIANBAO | 2006-10-19 | — | — | US | disclosed |
| US-7115598-B2 | Substituted 1,4-diazepines and uses thereof | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2006-10-03 | — | — | US | disclosed |
| EP-1656155-A2 | USE OF GENES DIFFERENTIALLY EXPRESSED DURING AGING OF LIVER FOR TREATMENT AND DIAGNOSIS | Ohio University (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1617807-A2 | SUBSTITUTED 1,4-DIAZEPINES AND USES THEREOF | Ortho-McNeil Pharmaceuticals, Inc. (US) | 2006-01-25 | — | — | EP | disclosed |
| US-20050227932-A1 | Combinational therapy involving a small molecule inhibitor of the MDM2: p53 interaction | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2005-10-13 | — | — | US | disclosed |
| US-H789-H | DESILVERING USING FERRIC COMPLEX SALT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4865959-A | HIGH SPEED COLORED IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0310125-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |
| EP-0295632-A2 | Silver halide color photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-12-21 | — | — | EP | disclosed |
| EP-0287073-A2 | Method for processing a silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-19 | — | — | EP | disclosed |
| US-4146537-A | Process for preparing imidazo[1,5-a][1,5]benzodiazepines | HOFFMANN-LA ROCHE INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4137229-A | NITROSATION, HYDROLYSIS, CARBOXYLATION, DECARBOXYLATION, HYDROGENATION, CONDENSATION, AMIDATION, CYCLIZATION, AMINATION | HOFFMANN-LA ROCHE INC. (US) | 1979-01-30 | — | — | US | disclosed |
| US-4111931-A | ANXIOLYTICS, ANTICONVULSANT, MUSCLE RELAXANT, SEDATIVE | HOFFMANN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4080323-A | ANXIOLYTICS, ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-RE28935-E | PSYCHOSEDATIVES, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235007-A1 | Substituted 1,4-diazepines and uses thereof | MDM2, TP53, RB1 | ALDH1A1 1841/4885MAPT 3530/4885GLA 3494/4885 |
| US-20050227932-A1 | Combinational therapy involving a small molecule inhibitor of the MDM2: p53 interaction | TP53, MDM2, TP53BP1 | ALDH1A1 2664/4885MAPT 1674/4885GLA 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.