SCHEMBL5152977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5152329	0.90	CXCR2 (0.51)	ITGA4KMT2AMEN1CXCR2MAPT
	SCHEMBL5151663	0.90	KMT2A (0.52)	ITGA4KMT2AMEN1CXCR2MAPT
	SCHEMBL5155588	0.90	NPC1 (0.50)	KMT2AMEN1MAPTNPC1RAB9A
	SCHEMBL5151777	0.86	ITGA4 (0.50)	ITGA4KMT2AMEN1MAPTNPC1
	SCHEMBL5149945	0.86	MEN1 (0.52)	ITGA4KMT2AMEN1CXCR2MAPT
	SCHEMBL5150127	0.81	ITGB1 (0.49)	ITGA4KMT2AMEN1MAPTNPC1
	SCHEMBL5155326	0.80	MEN1 (0.50)	KMT2AMEN1CXCR2MAPTNPC1
	SCHEMBL5881062	0.78	MEN1 (0.52)	KMT2AMEN1MAPTNPC1RAB9A
	SCHEMBL3933692	0.77	ALDH1A1 (0.51)	KMT2AMAPTNPC1RAB9ALMNA
	SCHEMBL30154480	0.77	ALDH1A1 (0.51)	KMT2AMAPTNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.