⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259243 | 0.73 | — | — | |
| SCHEMBL9313930 | 0.73 | — | — | |
| SCHEMBL3071643 | 0.72 | NOS3 (0.40) | — | |
| SCHEMBL1865028 | 0.71 | — | — | |
| SCHEMBL6964305 | 0.69 | — | — | |
| SCHEMBL2827696 | 0.69 | — | — | |
| SCHEMBL5212996 | 0.69 | — | — | |
| SCHEMBL15796358 | 0.67 | ALDH1A1 (0.46) | — | |
| SCHEMBL11507749 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL11623060 | 0.67 | TP53 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101555-A | REACTING EXCESS 2-METHYL-5-ETHYLPIPERIDINE | STAUFFER CHEMICAL COMPANY (US) | 1978-07-18 | — | — | US | claimed |
| US-20250257035-A1 | 1,4-Substituted Piperidine Derivatives | CEPHALON LLC | 2025-08-14 | — | — | US | disclosed |
| US-12098130-B2 | 1,4-substituted piperidine derivatives | 89BIO LTD (IL) | 2024-09-24 | — | — | US | disclosed |
| US-20230391723-A1 | 1,4-Substituted Piperidine Derivatives | CEPHALON LLC | 2023-12-07 | — | — | US | disclosed |
| US-11702388-B2 | 1,4-substituted piperidine derivatives | 89BIO LTD (IL) | 2023-07-18 | — | — | US | disclosed |
| US-20210230116-A1 | 1,4-Substituted Piperidine Derivatives | CEPHALON LLC | 2021-07-29 | — | — | US | disclosed |
| US-10851057-B2 | 1,4-substituted piperidine derivatives | 89BIO LTD (IL) | 2020-12-01 | — | — | US | disclosed |
| US-20190152913-A1 | 1,4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON LLC | 2019-05-23 | — | — | US | disclosed |
| US-10221135-B2 | 1,4-substituted piperidine derivatives | 89BIO LTD (IL) | 2019-03-05 | — | — | US | disclosed |
| US-20180179159-A1 | 1,4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON LLC | 2018-06-28 | — | — | US | disclosed |
| US-4478999-A | Process for the preparation of phenylpyridazine compounds | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1984-10-23 | — | — | US | disclosed |
| US-RE30495-E | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1981-01-27 | — | — | US | disclosed |
| US-4119431-A | Herbicidal effect of a mixture of cis and trans isomers of S-isopropyl-1-(5-ethyl-2-methylpiperidinecarbothioate) | STAUFFER CHEMICAL COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4119431-A | Herbicidal effect of a mixture of cis and trans isomers of S-isopropyl-1-(5-ethyl-2-methylpiperidinecarbothioate) | STAUFFER CHEMICAL COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4101555-A | REACTING EXCESS 2-METHYL-5-ETHYLPIPERIDINE | STAUFFER CHEMICAL COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4101555-A | REACTING EXCESS 2-METHYL-5-ETHYLPIPERIDINE | STAUFFER CHEMICAL COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4003909-A | [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-4002461-A | Substituted 2-azabicycloalkanes as selective herbicides | CIBA-GEIGY CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-3975538-A | O-ALKOXYCARBONYL-2-ALKOXY-1-NAPHTHOHYDROXAMATES | TAKEDA CHEMICAL INDUSTRIES, INC. (JA) | 1976-08-17 | — | — | US | disclosed |
| US-3936458-A | Substituted 2-azabicycloalkanes as selective herbicides | CIBA-GEIGY CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |