Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IL18 | Q14116 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181690 | 0.83 | PLA2G7 (0.46) | PLA2G7KDM4EALDH1A1USP2HPGD | |
| SCHEMBL5148195 | 0.81 | PNLIP (0.44) | ALDH1A1HPGDLMNASMN1; SMN2MEN1 | |
| SCHEMBL5149578 | 0.80 | MEN1 (0.55) | PLA2G7ALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL1075077 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1LMNAMEN1POLB | |
| SCHEMBL5553314 | 0.78 | ALDH1A1 (0.59) | PLA2G7KDM4EALDH1A1USP2HPGD | |
| SCHEMBL5151769 | 0.78 | PLA2G7 (0.49) | PLA2G7KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL28690740 | 0.77 | KDM4E (0.57) | PLA2G7KDM4EALDH1A1USP2LMNA | |
| SCHEMBL5149569 | 0.76 | TGM2 (0.56) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL5179974 | 0.76 | ALDH1A1 (0.46) | PLA2G7KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL28682193 | 0.76 | KDM4E (0.56) | PLA2G7KDM4EALDH1A1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |