SCHEMBL5154113

SCHEMBL5154113

O=S(=O)(c1cc(F)c(Cl)c(F)c1)c1cc(F)c(Cl)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.42
CA2 P00918 7/20 0.42
CA9 Q16790 6/20 0.42
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
VCAM1 P19320 1/20 0.38
CA7 P43166 3/20 0.36
CA12 O43570 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
PTGS2 P35354 2/20 0.33
CA3 P07451 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS1 P23219 1/20 0.33
HTR6 P50406 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5151223 0.78 CA1 (0.44) CA1CA2CA9VCAM1CA7
SCHEMBL28280990 0.74 PTGES2 (0.35) CA1CA2CA9CA7CA12
SCHEMBL4136925 0.74 HDAC1 (0.40) CA1CA2CA9ALDH1A1MAPK1
SCHEMBL5981674 0.74 CA1 (0.54) CA1CA2CA9ALDH1A1CYP3A4
SCHEMBL5028742 0.74 VCAM1 (0.38) CA1CA2CA9VCAM1CA7
SCHEMBL5151036 0.73 VCAM1 (0.47) CA1CA2CA9ALDH1A1CYP3A4
SCHEMBL4333676 0.72 CA1 (0.48) CA1CA2CA9ALDH1A1CYP3A4
SCHEMBL1958683 0.69 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL778133 0.69 CES2 (0.39) CA1CA9VCAM1CA12KMT2A
SCHEMBL4127316 0.69 VCAM1 (0.34) CA1CA2CA9ALDH1A1VCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070231671-A1 Catalyst Material For Use In Fuel Cell, Catalyst Membrane, Membrane Electrode Assembly and Fuel Cell FUJIFILM CORPORATION 2007-10-04 US disclosed