Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594062 | 0.92 | ALDH1A1 (0.53) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL4416351 | 0.90 | MAPT (0.56) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL9003269 | 0.83 | MAPT (0.70) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL1024700 | 0.80 | MAPT (0.61) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL5355772 | 0.80 | MAPT (0.61) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL4951837 | 0.80 | ALDH1A1 (0.73) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL3662904 | 0.79 | MAPT (0.59) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL28432645 | 0.79 | MAPT (0.59) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL11022003 | 0.79 | MAPT (0.59) | MAPTALDH1A1GLASMN1; SMN2HPGD | |
| SCHEMBL5157176 | 0.79 | MAPT (0.59) | MAPTALDH1A1GLASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739075-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with one or more hydroxyl, alkoxy and/or amino groups and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739075-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with one or more hydroxyl, alkoxy and/or amino groups and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | KRT18, PLOD3, DSP | MAPT 3579/4885ALDH1A1 298/4885GLA 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.