SCHEMBL5154375

SCHEMBL5154375

c1nc2c(ccc3ncsc32)s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
KDM4E B2RXH2 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DYRK1A Q13627 2/20 0.37
CLK1 P49759 2/20 0.32
PIK3CD O00329 1/20 0.32
PRKCB P05771 1/20 0.32
CSNK2A2 P19784 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CG P48736 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
HASPIN Q8TF76 1/20 0.32
DYRK2 Q92630 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8554868 0.98 ALDH1A1 (0.43) ALDH1A1HSD17B10NPC1RAB9AKDM4E
SCHEMBL2722669 0.78 ALDH1A1 (0.46) ALDH1A1HSD17B10NPC1RAB9AKDM4E
SCHEMBL11565679 0.76 ALDH1A1 (0.41) ALDH1A1HSD17B10NPC1RAB9ATDP1
SCHEMBL9532220 0.69 KDM4E (0.33) ALDH1A1HSD17B10NPC1RAB9AKDM4E
SCHEMBL15893886 0.69 RAB9A (0.43) ALDH1A1NPC1RAB9AKDM4EHKDC1
SCHEMBL8627135 0.68 MELK (0.37) ALDH1A1HSD17B10NPC1RAB9AKDM4E
SCHEMBL140968 0.68 LMNA (0.54) ALDH1A1NPC1RAB9AKDM4ETDP1
SCHEMBL29467245 0.68 LMNA (0.38) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL9980542 0.67 EGFR (0.37) ALDH1A1HSD17B10PIK3CDPIK3CA
Hydrochloric Acid SCHEMBL28958656 0.67 LMNA (0.52) ALDH1A1NPC1RAB9AKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0145337-B1 ELECTROCHROMIC DEVICES CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-08-08 EP claimed
EP-0096723-B1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-10 EP claimed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US claimed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP claimed
EP-0096723-A1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS. CHEVRON RES (US) 1983-12-28 EP claimed
WO-1983002368-A1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RES (US) 1983-07-07 WO claimed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
EP-1361477-B1 Process for chemically sensitizing a green-sensitive silver halide photographic emulsion and photographic material containing said emulsion FERRANIA TECHNOLOGIES SPA (IT) 2007-01-17 EP disclosed
EP-1361477-A1 Process for chemically sensitizing a green-sensitive silver halide photographic emulsion and photographic material containing said emulsion FERRANIA S.p.A. (IT) 2003-11-12 EP disclosed
US-5024928-A Containing monomethine cyanine dye and thiazole quartnary salt MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-06-18 US disclosed
EP-0145337-B1 ELECTROCHROMIC DEVICES CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-08-08 EP disclosed
US-4849327-A Silver halide light-sensitive material comprising benzo-bis-thiazole quaternary salts as antifogging agents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-18 US disclosed
EP-0096723-B1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-10 EP disclosed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US disclosed
EP-0126064-A4 ELECTROACTIVE POLYMERS. CHEVRON RES (US) 1985-07-01 EP disclosed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP disclosed
US-4522745-A NITROGEN CONTAINING RING;POSSIBLY CONTAINING OXYGEN, SULFUR, SELENIUM OR TELLURIUM CHEVRON RESEARCH COMPANY (US) 1985-06-11 US disclosed
EP-0126064-A1 ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1984-11-28 EP disclosed
WO-1984002030-A1 ELECTROACTIVE POLYMERS CHEVRON RES (US) 1984-05-24 WO disclosed