Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL4602907 | 0.82 | FDPS (0.40) | FDPSMETAP1ANPEP | |
| Butane SCHEMBL1088110 | 0.78 | LMNA (0.55) | LMNA | |
| Propionaldehyde SCHEMBL56362 | 0.78 | LMNA (0.60) | LMNA | |
| Propionaldehyde SCHEMBL8906570 | 0.78 | LMNA (0.60) | LMNA | |
| Phosphoric Acid SCHEMBL368038 | 0.77 | LMNA (0.67) | LMNAFDPSMEN1CYP1A2KMT2A | |
| Butane SCHEMBL818136 | 0.75 | LMNA (0.63) | LMNA | |
| Butane SCHEMBL2557609 | 0.75 | LMNA (0.63) | LMNA | |
| Butane SCHEMBL11232709 | 0.74 | LMNA (0.55) | LMNA | |
| SCHEMBL629168 | 0.73 | LMNA (0.60) | LMNA | |
| Butane SCHEMBL8312214 | 0.73 | LMNA (0.60) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1262476-B1 | PROCESSES FOR PREPARING QUINOLINE DERIVATIVES AND INTERMEDIATES THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-6855824-B2 | Processes for preparing quinoline derivatives and intermediates thereof | KURARAY CO., LTD. (JP) | 2005-02-15 | — | — | US | disclosed |
| US-20030125355-A1 | Processes for preparing quinoline derivatives and intermedias thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-03 | — | — | US | disclosed |
| EP-1262476-A1 | PROCESSES FOR PREPARING QUINOLINE DERIVATIVES AND INTERMEDIATES THEREOF | KURARAY CO., LTD. (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-5096919-A | Pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-4960787-A | LIPOXYGENASE INHIBITORS; ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0378991-A1 | Certain pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125355-A1 | Processes for preparing quinoline derivatives and intermedias thereof | NQO1, ADH1B, IDH3B | LMNA 620/4885FDPS 146/4885MEN1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.