⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185880 | 0.85 | — | — | |
| SCHEMBL23048409 | 0.79 | NLRP3 (0.32) | — | |
| SCHEMBL12199033 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL10276525 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL3159235 | 0.76 | APAF1 (0.40) | — | |
| SCHEMBL3670921 | 0.76 | APAF1 (0.40) | — | |
| SCHEMBL6865358 | 0.76 | MAP3K7 (0.30) | — | |
| SCHEMBL12202544 | 0.76 | MAP3K7 (0.30) | — | |
| SCHEMBL3156583 | 0.76 | APAF1 (0.40) | — | |
| SCHEMBL12568355 | 0.76 | MAP3K7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472232-B1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2007-01-24 | — | — | EP | disclosed |
| EP-1472232-A4 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2006-02-01 | — | — | EP | disclosed |
| EP-1472232-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | Yuhan Corporation (KR) | 2004-11-03 | — | — | EP | disclosed |
| US-6706888-B2 | REACTING A 3-HALOTETRAHYDROFURAN OR TETRAHYDROPYRAN COMPOUND WITH FORMAMIDINE OR ITS SALT IN THE PRESENCE OF A BASE TO PRODUCE A 3-(1H-IMIDAZOL-4-YL)PROPANOL DERIVATIVE; EFFICIENCY; INTERMEDIATES; ANTICARCINOGENIC AGENTS; VIRICIDES; | YUHAN CORPORATION (KR) | 2004-03-16 | — | — | US | disclosed |
| US-20030153769-A1 | Processes for preparing imidazole derivatives and salts thereof | YUHAN CORPORATION | 2003-08-14 | — | — | US | disclosed |
| WO-2003066600-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORPORATION (KR) | 2003-08-14 | — | — | WO | disclosed |