Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150706 | 0.88 | HRH3 (0.47) | HRH3ALOX15ACHETPH1L3MBTL1 | |
| SCHEMBL5151662 | 0.87 | ALDH1A1 (0.44) | HRH3ALOX15ACHETPH1L3MBTL1 | |
| SCHEMBL7960935 | 0.87 | SLC7A5 (0.48) | PKMTPH1SLC7A5ALDH1A1MMP8 | |
| SCHEMBL5151172 | 0.87 | TPH1 (0.39) | PKMTPH1L3MBTL1SLC7A5ALDH1A1 | |
| SCHEMBL5154261 | 0.84 | HDAC1 (0.47) | HDAC8HDAC6PKMALOX15ACHE | |
| SCHEMBL9967935 | 0.82 | SLC7A5 (0.44) | PKMTPH1SLC7A5ALDH1A1LMNA | |
| SCHEMBL14139328 | 0.82 | SLC7A5 (0.44) | PKMTPH1L3MBTL1SLC7A5ALDH1A1 | |
| SCHEMBL21117856 | 0.82 | SLC7A5 (0.44) | PKMTPH1SLC7A5ALDH1A1LMNA | |
| SCHEMBL20543461 | 0.82 | SLC7A5 (0.44) | PKMTPH1SLC7A5ALDH1A1LMNA | |
| L-Tyrosine Ethylester SCHEMBL9327871 | 0.81 | SLC7A5 (0.61) | HDAC8TPH1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1297546-C | N- (arylsulfonyl) -beta-amino acid derivatives with substituted aminomethyl group, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2007-01-31 | — | — | CN | disclosed |
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| CN-1541211-A | Derivatives of N-(arylsulfonyl) beta-aminoacids comprising substituted aminomethyl group, prepn. method thereof and pharmaceutical compsns. contg same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-10-27 | — | — | CN | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |