Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592278 | 0.97 | HTR1A (0.68) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5592228 | 0.96 | HTR1A (0.67) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5592230 | 0.92 | HTR1A (0.74) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5610871 | 0.91 | HTR1A (0.73) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4877989 | 0.87 | HTR7 (0.86) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5813172 | 0.86 | ADRA1A (0.61) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL4918970 | 0.86 | HTR7 (0.84) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5808327 | 0.85 | DRD2 (0.77) | HTR1AMEN1HTR7KMT2AADRA1A | |
| SCHEMBL7671770 | 0.85 | HTR7 (0.91) | HTR1AMEN1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5820928 | 0.84 | DRD2 (0.75) | HTR1AMEN1HTR7KMT2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746998-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES, LTD. (IN) | 2007-01-31 | — | — | EP | claimed |
| WO-2005092341-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-06 | — | — | WO | claimed |