SCHEMBL5156

SCHEMBL5156

[CH]1Nc2ccccc2O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16398546 0.75 ALOX5 (0.41)
SCHEMBL224635 0.75 ALOX5 (0.41)
Hydrochloric Acid SCHEMBL6760431 0.73 ALOX5 (0.39)
Hydrochloric Acid SCHEMBL7159864 0.73 ALOX5 (0.39)
Biphenyl SCHEMBL12979723 0.69 ALDH1A1 (0.36)
SCHEMBL7441406 0.69 ALOX5 (0.35)
SCHEMBL18209132 0.68 ALOX5 (0.34)
SCHEMBL1938607 0.65 ALOX5 (0.32)
SCHEMBL18835 0.64 ALOX5 (0.39)
SCHEMBL17948075 0.64 ALOX5 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744824-B2 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds 1ST Biotherapeutics, Inc. (KR) 2023-09-05 US claimed
US-11713312-B2 Substituted bicyclic compounds as farnesoid X receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2023-08-01 US claimed
EP-4214207-A1 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS 1st Biotherapeutics, Inc. (KR) 2023-07-26 EP claimed
CN-116457355-A 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds 第一生物治疗股份有限公司 2023-07-18 CN claimed
CN-116396262-A Spiro-containing asymmetric aromatic diamine for polyimide and preparation method and application thereof 兰州大学 2023-07-07 CN claimed
CN-116003433-A Organic photosensitive molecule with spectral response reaching infrared region and application thereof 广州光达创新科技有限公司 2023-04-25 CN claimed
CN-115819413-A Carbazole-based small-molecule compound, method and organic all-optical synapse based on illumination history-dependent fluorescence intensity mechanism 中国科学院大学 2023-03-21 CN claimed
CN-115724826-A Heterocyclic compound and application thereof 上海八亿时空先进材料有限公司 2023-03-03 CN claimed
CN-114891027-A Infrared-response N-type organic molecule and application thereof 广州光达创新科技有限公司 2022-08-12 CN claimed
US-11352316-B2 Opioid receptor modulators and products and methods related thereto EPIODYNE, INC. (US) 2022-06-07 US claimed
EP-0361262-A1 Preparation of poly(aryl ether/thioether) segmented block copolymers THE DOW CHEMICAL COMPANY (US) 1990-04-04 EP claimed
EP-0353478-A1 Preparation of poly(aryl ether/thioether)-poly (aryl carbonate) block copolymers THE DOW CHEMICAL COMPANY (US) 1990-02-07 EP claimed
EP-0233140-B1 LUBRICANT ADDITIVES CONTAINING SULPHUR AND NITROGEN CIBA-GEIGY AG (CH) 1989-11-08 EP claimed
EP-0166696-B1 LUBRICANT ADDITIVES CIBA-GEIGY AG (CH) 1989-07-19 EP claimed
US-4784929-A LATENT IMAGES MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1988-11-15 US claimed
EP-0120589-B1 IMIDAZO-HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-08 EP claimed
EP-0233140-A1 Lubricant additives containing sulphur and nitrogen CIBA-GEIGY AG (CH) 1987-08-19 EP claimed
US-4621084-A CARDIOTONIC, ANTIULCER FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-11-04 US claimed
EP-0166696-A2 Lubricant additives CIBA-GEIGY AG (CH) 1986-01-02 EP claimed
EP-0120589-A1 Imidazo-heterocyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-03 EP claimed