Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224635 | 0.87 | ALOX5 (0.41) | ALOX5PARP1 | |
| Hydrochloric Acid SCHEMBL6760431 | 0.85 | ALOX5 (0.39) | ALOX5PARP1 | |
| Hydrochloric Acid SCHEMBL7159864 | 0.85 | ALOX5 (0.39) | ALOX5PARP1 | |
| Biphenyl SCHEMBL12979723 | 0.80 | ALDH1A1 (0.36) | ALOX5PARP1 | |
| SCHEMBL18209132 | 0.78 | ALOX5 (0.34) | ALOX5PARP1 | |
| SCHEMBL1938607 | 0.76 | ALOX5 (0.32) | ALOX5 | |
| Trifluoroacetic Acid SCHEMBL2072798 | 0.72 | CES1 (0.35) | ALOX5 | |
| Trifluoroacetic Acid SCHEMBL2072797 | 0.72 | CES1 (0.35) | ALOX5 | |
| SCHEMBL5156 | 0.69 | — | — | |
| SCHEMBL27266539 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417671-A2 | 3,4,5,6-Tetrahydro-2H-1,7,4-Benzodioxazonines as cardiovascular agents | BERLEX LABORATORIES, INC. (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4966967-A | 3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonines as cardiovascular agents | BERLEX LABORATORIES, INC. (US) | 1990-10-30 | — | — | US | disclosed |