Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL169844 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1MAPTKMT2AATM | |
| Acetic Acid Pentyl Ester SCHEMBL19859042 | 0.79 | ALDH1A1 (0.71) | ALDH1A1ATMFAAHTSHRNAAA | |
| Hexyl Acetate SCHEMBL28321779 | 0.78 | ALDH1A1 (0.77) | ALDH1A1FAAHTSHRNAAADGKA | |
| Heptane SCHEMBL6963689 | 0.78 | ALDH1A1 (0.76) | ALDH1A1FAAHTSHRNAAADGKA | |
| Hexyl Acetate SCHEMBL28209353 | 0.77 | ALDH1A1 (0.68) | ALDH1A1FAAHTSHRNAAACES2 | |
| Acetic Acid Pentyl Ester SCHEMBL9551991 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ATMFAAHTSHRNAAA | |
| Ethyl Acetate SCHEMBL2271896 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2AATM | |
| Ethyl Acetate SCHEMBL4621152 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2AATM | |
| SCHEMBL20711059 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1MAPTKMT2AATM | |
| Nonylacetate SCHEMBL309051 | 0.76 | ALDH1A1 (0.81) | ALDH1A1FAAHTSHRNAAADGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166140-B | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| CN-116354815-A | Method for efficiently purifying cannabidiol from industrial cannabis sativa leaves | 云南绿新生物药业有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113166140-A | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20200411933-A1 | SOLUBLE OXYGEN EVOLVING CATALYSTS FOR RECHARGEABLE METAL-AIR BATTERIES | LIOX POWER INC (US) | 2020-12-31 | — | — | US | disclosed |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2020-10-29 | — | — | US | disclosed |
| EP-2561573-B1 | SOLUBLE OXYGEN EVOLVING CATALYSTS FOR RECHARGEABLE METAL-AIR BATTERIES | LIOX POWER INC (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2020027704-A1 | CDK8/19 INHIBITORS | ЗАКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "БИОКАД" | 2020-02-06 | — | — | WO | disclosed |
| CN-106324137-B | A kind of chromatogram quantitative analysis of the liquid phase method of 2- ethyl hydrazine and tetrahydro -2- ethyl hydrazine in hydrogen-peroxide working solution | 湘潭大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-106324137-B | A kind of chromatogram quantitative analysis of the liquid phase method of 2- ethyl hydrazine and tetrahydro -2- ethyl hydrazine in hydrogen-peroxide working solution | 湘潭大学 | 2019-09-27 | — | — | CN | disclosed |
| US-7585875-B2 | Substituted pyrazolo[1,5-a]pyridine compounds and their methods of use | AVIGEN, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| CN-101401880-A | Quality control method for Ditong rhinitis drop and mist | BOKE PHARMACEUTICAL CO LTD (CN) | 2009-04-08 | — | — | CN | disclosed |
| EP-2038279-A2 | SUBSTITUTED PYRAZOLO [1,5- ALPHA] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | Avigen, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20080070912-A1 | Substituted pyrazolo [1,5-a] pyridine compounds and their methods of use | AVIGEN, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| WO-2007146087-A2 | SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | AVIGEN, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20060167044-A1 | Piperidine derivatives and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| US-5585501-A | Method for the reduction of allyl alcohols | SHIONOGI & CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0543526-B1 | Method for the reduction of allyl alcohols | SHIONOGI & CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| EP-0543526-A1 | Method for the reduction of allyl alcohols | SHIONOGI & CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885MEN1 3247/4885MAPT 4568/4885 |
| US-20060167044-A1 | Piperidine derivatives and their use as anti-inflammatory agents | CCR1, CCR2, CCR3 | ALDH1A1 296/4885MEN1 4827/4885MAPT 3394/4885 |
| US-20080070912-A1 | Substituted pyrazolo [1,5-a] pyridine compounds and their methods of use | PNPO, PDXK, P2RX5 | ALDH1A1 549/4885MEN1 1617/4885MAPT 2050/4885 |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | PREP, UNG, DPP4 | ALDH1A1 1478/4885MEN1 3030/4885MAPT 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.