Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 17/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5449940 | 0.98 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4051249 | 0.87 | OPRL1 (0.63) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL4056476 | 0.85 | OPRL1 (0.61) | OPRL1OPRM1OPRK1 | |
| SCHEMBL7814234 | 0.82 | RAB9A (0.42) | OPRL1OPRM1 | |
| SCHEMBL19151630 | 0.81 | OPRL1 (0.55) | OPRL1OPRM1OPRK1 | |
| SCHEMBL5454663 | 0.81 | OPRL1 (0.51) | OPRL1OPRM1OPRK1 | |
| SCHEMBL5382074 | 0.80 | OPRL1 (0.68) | OPRL1OPRM1OPRK1 | |
| SCHEMBL2780290 | 0.79 | OPRL1 (0.59) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1041409 | 0.78 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL9682242 | 0.78 | MEN1 (0.48) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751095-B1 | SUBSTITUTED CYCLOHEXYLCARBOXYLIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2014-06-18 | — | — | EP | claimed |
| US-7241802-B2 | Substituted cyclohexylcarboxylic acid amide compounds | GRUENENTHAL GMBH (DE) | 2007-07-10 | — | — | US | claimed |
| US-20070105941-A1 | Substituted cyclohexylcarboxylic acid amide compounds | GRUENENTHAL GMBH (DE) | 2007-05-10 | — | — | US | claimed |
| CN-108602777-A | 3- ((miscellaneous -) aryl)-alkyl -8- amino -2- oxos -1,3- aza-spiro-[4.5]-decane derivative | 格吕伦塔尔有限公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-1751095-B1 | SUBSTITUTED CYCLOHEXYLCARBOXYLIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2014-06-18 | — | — | EP | disclosed |
| US-7241802-B2 | Substituted cyclohexylcarboxylic acid amide compounds | GRUENENTHAL GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| US-20070105941-A1 | Substituted cyclohexylcarboxylic acid amide compounds | GRUENENTHAL GMBH (DE) | 2007-05-10 | — | — | US | disclosed |
| EP-1751095-A1 | SUBSTITUTED CYCLOHEXYLCARBOXYLIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110977-A1 | SUBSTITUTED CYCLOHEXYLCARBOXYLIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105941-A1 | Substituted cyclohexylcarboxylic acid amide compounds | OPRL1, OPRK1, HCAR1 | OPRL1 1/4885OPRM1 5/4885OPRK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.