Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19770698 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL17824836 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL6912228 | 0.73 | VCAM1 (0.49) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL8407409 | 0.72 | ALDH1A1 (0.48) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL30048240 | 0.72 | VCAM1 (0.49) | VCAM1 | |
| SCHEMBL2968414 | 0.71 | CA1 (0.42) | ALDH1A1CA2VCAM1 | |
| SCHEMBL8094382 | 0.69 | ALDH1A1 (0.45) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL3999963 | 0.69 | ATM (0.48) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL295477 | 0.69 | ALDH1A1 (0.38) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL17430868 | 0.69 | ESR1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740522-A2 | BISPHENYL COMPOUNDS USEFUL AS VITAMIN D SB 3 /SB RECEPTOR AGONISTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060025474-A1 | Bisphenyl compounds useful as vitamin D3 receptor agonists | CHUGAI SEIYAKU KABUSHIKA KAISHA (JP) | 2006-02-02 | — | — | US | disclosed |
| WO-2005087700-A2 | BISPHENYL COMPOUNDS USEFUL AS VITAMIN D3 RECEPTOR AGONISTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025474-A1 | Bisphenyl compounds useful as vitamin D3 receptor agonists | VDR, CYP2R1, CYP24A1 | CYP3A4 476/4885CYP2D6 450/4885ALDH1A1 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.