SCHEMBL5157734

SCHEMBL5157734

CCCCOc1ccccc1C(=O)OC(=O)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
NR1I2 O75469 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
ALDH1A1 P00352 2/20 0.49
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
PTPN11 Q06124 2/20 0.46
FAAH O00519 6/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5155893 0.93 ALDH1A1 (0.50) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL4395023 0.89 MAPT (0.56) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL1006617 0.89 LMNA (0.59) MEN1KMT2ALMNAMAPTNR1I2
Bicarbonate SCHEMBL29983479 0.87 MAPT (0.55) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL4343858 0.87 ESR1 (0.51) MEN1KMT2ALMNAMAPTL3MBTL1
Bicarbonate SCHEMBL7114860 0.86 ESR1 (0.50) MEN1KMT2ALMNAMAPTL3MBTL1
SCHEMBL28811038 0.85 LMNA (0.62) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL5157380 0.84 MAPT (0.45) MEN1KMT2ALMNAMAPTL3MBTL1
SCHEMBL2169334 0.83 LMNA (0.65) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL27915224 0.83 LMNA (0.65) MEN1KMT2ALMNAMAPTNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7259223-B2 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY (US) 2007-08-21 US disclosed
EP-1360220-B1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GEN ELECTRIC (US) 2007-01-31 EP disclosed
US-20040220352-A1 Process for the production of polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2004-11-04 US disclosed
EP-1360220-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-11-12 EP disclosed
US-20020132957-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2002-09-19 US disclosed
WO-2002060855-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-08-08 WO disclosed