Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155596 | 0.86 | SMPD1 (0.55) | KMT2AGAAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL5157983 | 0.81 | GAA (0.46) | KMT2AGAAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL13333716 | 0.81 | BCHE (0.41) | KMT2AGAAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL2764944 | 0.81 | CYP4F2 (0.45) | KMT2ACYP4F2CYP4A11ATMSPHK2 | |
| SCHEMBL19382251 | 0.79 | CYP4F2 (0.47) | KMT2ACYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL9717443 | 0.77 | GAA (0.77) | KMT2AGAAHSD17B10SMPD1ATM | |
| SCHEMBL5157580 | 0.77 | GAA (0.46) | KMT2AGAAHSD17B10SMPD1ATM | |
| SCHEMBL13323833 | 0.76 | HPGD (0.46) | KMT2ACYP4F2CYP4A11ATMLMNA | |
| SCHEMBL1880076 | 0.75 | SPHK2 (0.52) | CYP4F2CYP4A11SMPD1SPHK2SPHK1 | |
| SCHEMBL1880075 | 0.75 | SPHK2 (0.52) | CYP4F2CYP4A11SMPD1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |