Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5601823 | 0.84 | HSPD1 (0.42) | TSHRALDH1A1HSPD1BLMHSPE1 | |
| SCHEMBL3027443 | 0.77 | LMNA (0.40) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL8583429 | 0.76 | CYP2D6 (0.34) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL18936928 | 0.75 | CA12 (0.36) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL9702992 | 0.74 | HSPD1 (0.32) | HSPD1BLMHSPE1CA12CA9 | |
| SCHEMBL5812141 | 0.74 | CYP2D6 (0.32) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL18798914 | 0.71 | ALDH1A1 (0.46) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL8581959 | 0.70 | KDM5A (0.35) | CYP2D6TSHRCYP2C19HIF1AHSPD1 | |
| SCHEMBL4998501 | 0.70 | CYP2D6 (0.39) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL8583397 | 0.68 | TSHR (0.38) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159334-B1 | PROCESS FOR THE MANUFACTURE OF FUNCTIONALIZED POLYPHENYLENE ETHERS | GEN ELECTRIC (US) | 2007-01-17 | — | — | EP | disclosed |