SCHEMBL515796

SCHEMBL515796

CCOC(=O)C(C)=C(CC)NC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GLO1 Q04760 1/20 0.41
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
EGLN1 Q9GZT9 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.35
ALOX15 P16050 1/20 0.34
ABCB1 P08183 1/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9642404 0.82 EGLN1 (0.41) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL29138970 0.79 EGLN1 (0.39) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL27248414 0.79 ALOX15 (0.40) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL28036731 0.78 ALDH1A1 (0.44) MAPTALDH1A1LMNAHSD17B10GLO1
Dimethylamine SCHEMBL22500818 0.77 MAPT (0.47) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL5611940 0.77 ALDH1A1 (0.58) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL11141816 0.77 ALDH1A1 (0.58) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL5611950 0.77 ALDH1A1 (0.58) MAPTALDH1A1LMNAHSD17B10GLO1
SCHEMBL26906441 0.76 ACHE (0.46) EGLN1TSHRHTT
SCHEMBL844488 0.73 TDP1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150094448-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. 2015-04-02 US claimed
EP-2847249-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES Medipacs, Inc. (US) 2015-03-18 EP claimed
WO-2013138524-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. (US) 2013-09-19 WO claimed
US-10000605-B2 Smart polymer materials with excess reactive molecules MEDIPACS, INC. (US) 2018-06-19 US disclosed
US-20170069824-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS MEDIPACS INC (US) 2017-03-09 US disclosed
US-9500186-B2 High surface area polymer actuator with gas mitigating components MEDIPACS, INC. (US) 2016-11-22 US disclosed
US-20160206817-A1 LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS MEDIPACS INC (US) 2016-07-21 US disclosed
US-9238102-B2 Low profile actuator and improved method of caregiver controlled administration of therapeutics MEDIPACS, INC. (US) 2016-01-19 US disclosed
US-20150094448-A1 SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES MEDIPACS, INC. 2015-04-02 US disclosed
US-20140221913-A1 LOW PROFILE INFUSION PUMP WITH ANTI DRUG DIVERSION AND ACTIVE FEEDBACK MECHANISMS MEDIPACS, INC. (US) 2014-08-07 US disclosed
EP-2760497-A1 LOW PROFILE INFUSION PUMP WITH ANTI DRUG DIVERSION AND ACTIVE FEEDBACK MECHANISMS Medipacs, Inc. (US) 2014-08-06 EP disclosed
WO-2013049070-A1 LOW PROFILE INFUSION PUMP WITH ANTI DRUG DIVERSION AND ACTIVE FEEDBACK MECHANISMS MEDIPACS, INC. (US) 2013-04-04 WO disclosed
EP-2531549-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS Medipacs, Inc. (US) 2012-12-12 EP disclosed
US-20120191060-A1 LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS MEDIPACS, INC. 2012-07-26 US disclosed
US-20120029430-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS MEDIPACS, INC. 2012-02-02 US disclosed
WO-2011094747-A1 HIGH SURFACE AREA POLYMER ACTUATOR WITH GAS MITIGATING COMPONENTS MEDIPACS, INC. (US) 2011-08-04 WO disclosed
WO-2011032011-A1 LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS MEDIPACS, INC. (US) 2011-03-17 WO disclosed
US-4713265-A RAPID CURING AT LOW TEMPERATURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-15 US disclosed
EP-0224915-A2 Amine vapor curable coating composition of an acrylic polymer and a polyisocyanate E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-06-10 EP disclosed
US-4659799-A Amine vapor curable coating composition of an acrylic polymer and a polyisocyanate E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-21 US disclosed