Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906441 | 0.89 | ACHE (0.46) | EGLN1EPHX1HTTTSHR | |
| SCHEMBL9642404 | 0.85 | EGLN1 (0.41) | EGLN1MAPTGLO1ALDH1A1LMNA | |
| SCHEMBL515796 | 0.79 | MAPT (0.41) | EGLN1MAPTGLO1ALDH1A1LMNA | |
| SCHEMBL2012446 | 0.76 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL9113646 | 0.75 | MMP1 (0.38) | MAPTALDH1A1LMNANPSR1MMP1 | |
| SCHEMBL27248414 | 0.74 | ALOX15 (0.40) | EGLN1MAPTGLO1ALDH1A1LMNA | |
| SCHEMBL24873009 | 0.74 | EGLN1 (0.61) | EGLN1MAPTALDH1A1MGAMGAA | |
| SCHEMBL5611950 | 0.72 | ALDH1A1 (0.58) | EGLN1MAPTGLO1ALDH1A1LMNA | |
| SCHEMBL5611940 | 0.72 | ALDH1A1 (0.58) | EGLN1MAPTGLO1ALDH1A1LMNA | |
| SCHEMBL11141816 | 0.72 | ALDH1A1 (0.58) | EGLN1MAPTGLO1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402304-A | Acid-activated bioorthogonal click amphiphilic polymer and nanoparticle, preparation method and application thereof | 华东师范大学 | 2024-01-16 | — | — | CN | disclosed |