Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20298234 | 0.84 | CTRB1 (0.61) | CTRB1ITGB3ITGA2BSYKCTSK | |
| SCHEMBL29641210 | 0.84 | CTRB1 (0.61) | CTRB1ITGB3ITGA2BSYKCTSK | |
| SCHEMBL20783325 | 0.84 | CTRB1 (0.61) | CTRB1ITGB3ITGA2BSYKCTSK | |
| SCHEMBL29440228 | 0.84 | KYNU (0.56) | ITGB3ITGA2BPSMB1PSMB5PSMB2 | |
| SCHEMBL4829896 | 0.83 | CTRB1 (0.68) | CTRB1SYKCTSKTACR1LMNA | |
| SCHEMBL11668895 | 0.83 | CTRB1 (0.54) | CTRB1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL10773754 | 0.83 | CTRB1 (0.54) | CTRB1ITGB3ITGA2BPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL31236441 | 0.83 | CTRB1 (0.57) | CTRB1ITGB3ITGA2BSYKCTSK | |
| Hydrochloric Acid SCHEMBL31375007 | 0.82 | KYNU (0.55) | ITGB3ITGA2BPSMB1PSMB5PSMB2 | |
| Hydrochloric Acid SCHEMBL31376778 | 0.82 | KYNU (0.55) | ITGB3ITGA2BPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189879-B2 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | SCHERING AG (DE) | 2007-03-13 | — | — | US | disclosed |
| EP-1748977-A1 | METHOD FOR PRODUCING 1-HYDROXYMETHYL-1,3,5-TRIAZAPENTANE, TRIHYDROCHLORIDE | Schering Aktiengesellschaft (DE) | 2007-02-07 | — | — | EP | disclosed |
| US-20060014983-A1 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-01-19 | — | — | US | disclosed |
| WO-2005115968-A1 | METHOD FOR PRODUCING 1-HYDROXYMETHYL-1,3,5-TRIAZAPENTANE, TRIHYDROCHLORIDE | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014983-A1 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | CYP8B1, HADHA, DHPS | CTRB1 1472/4885ITGB3 4661/4885ITGA2B 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.