SCHEMBL5158591

SCHEMBL5158591

CCOC(=O)C1C(=O)Cc2ccc(-c3ccccc3)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
RAB9A P51151 1/20 0.41
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
TP53 P04637 1/20 0.38
DHODH Q02127 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998760 0.83 HDAC4 (0.44) L3MBTL1MEN1KMT2ATSHRTP53
SCHEMBL4970905 0.82 ATM (0.43) L3MBTL1ATMRAB9AMEN1KMT2A
SCHEMBL603697 0.80 MTNR1B (0.43) TSHRALDH1A1KDM4EMAPT
SCHEMBL4974228 0.73 MEN1 (0.41) RAB9AMEN1KMT2ATP53ALDH1A1
SCHEMBL18387947 0.72 RAB9A (0.44) L3MBTL1ATMRAB9ACHRM2CHRM4
SCHEMBL4969649 0.72 HPGD (0.43) L3MBTL1CHRM2CHRM1CHRM3MEN1
SCHEMBL2653688 0.71 TSHR (0.53) L3MBTL1ATMRAB9ACHRM2CHRM4
SCHEMBL26688084 0.71 L3MBTL1 (0.51) L3MBTL1ATMRAB9ACHRM2CHRM4
SCHEMBL4972012 0.71 ALDH1A1 (0.41) L3MBTL1RAB9AMEN1KMT2ATSHR
SCHEMBL18387945 0.70 RAB9A (0.42) L3MBTL1ATMRAB9ACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1153944-B1 PROPYLENE POLYMER, MOLDED OBJECT THEREOF IDEMITSU KOSAN CO (JP) 2007-01-31 EP disclosed
US-6800706-B1 TRANSPARENT, LOW-TEMPERATURE HEAT-SEALABILITY AND WEAR RESISTANCE; WRAPPING AND PACKAGING FILMS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-10-05 US disclosed
EP-1153944-A1 PROPYLENE POLYMER, MOLDED OBJECT THEREOF, AND PROCESS FOR PRODUCING PROPYLENE POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-11-14 EP disclosed