Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159113 | 0.90 | VCP (0.40) | VCPRAB9ANPC1MEN1KMT2A | |
| SCHEMBL5001897 | 0.86 | RAB9A (0.47) | MKNK1MKNK2RAB9ANPC1MEN1 | |
| SCHEMBL5159104 | 0.82 | DYRK1A (0.45) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL5001904 | 0.73 | RAB9A (0.48) | MKNK1MKNK2RAB9ANPC1MEN1 | |
| SCHEMBL716174 | 0.72 | KDM4E (0.54) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL720660 | 0.70 | NPC1 (0.44) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL716307 | 0.70 | KDM4E (0.52) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL714837 | 0.68 | NPC1 (0.53) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL718122 | 0.68 | ABL1 (0.58) | RAB9ANPC1ABL1EGFRERBB2 | |
| SCHEMBL27904707 | 0.68 | RAB9A (0.52) | MKNK1MKNK2RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746990-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB Science (FR) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112920-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB SCIENCE (FR) | 2005-12-01 | — | — | WO | disclosed |