Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716174 | 0.90 | KDM4E (0.54) | DYRK1ADYRK1BCLK1HASPINRAB9A | |
| SCHEMBL5159113 | 0.84 | VCP (0.40) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL714193 | 0.83 | GAA (0.58) | RAB9ANPC1TP53MEN1KMT2A | |
| SCHEMBL5159101 | 0.82 | VCP (0.39) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL716307 | 0.78 | KDM4E (0.52) | DYRK1ARAB9ANPC1KDM4EMEN1 | |
| SCHEMBL718339 | 0.77 | RAB9A (0.44) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL714837 | 0.75 | NPC1 (0.53) | RAB9ANPC1KDM4ETP53MEN1 | |
| SCHEMBL718122 | 0.75 | ABL1 (0.58) | CLK1RAB9ANPC1ABL1PDGFRB | |
| SCHEMBL720659 | 0.75 | ABL1 (0.59) | RAB9ANPC1KDM4ETP53MEN1 | |
| SCHEMBL718546 | 0.74 | ABL1 (0.49) | KDM4EABL1PDGFRBBCRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746990-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB Science (FR) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112920-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB SCIENCE (FR) | 2005-12-01 | — | — | WO | disclosed |