Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159101 | 0.90 | VCP (0.39) | VCPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL5001904 | 0.84 | RAB9A (0.48) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL5159104 | 0.84 | DYRK1A (0.45) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL5001897 | 0.75 | RAB9A (0.47) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL716174 | 0.73 | KDM4E (0.54) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL720660 | 0.69 | NPC1 (0.44) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL714193 | 0.68 | GAA (0.58) | VCPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL716307 | 0.67 | KDM4E (0.52) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL718339 | 0.67 | RAB9A (0.44) | KMT2AMEN1NPC1RAB9ACASP3 | |
| SCHEMBL6269851 | 0.67 | CYP19A1 (0.49) | KMT2AMEN1NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746990-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB Science (FR) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112920-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB SCIENCE (FR) | 2005-12-01 | — | — | WO | disclosed |