SCHEMBL515973

SCHEMBL515973

CCc1cccc(OCCO)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.59
ALDH1A1 P00352 7/20 0.58
KDM4E B2RXH2 5/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPK1 P28482 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
TSHR P16473 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
RECQL P46063 1/20 0.53
GAA P10253 1/20 0.51
SOD1 P00441 1/20 0.49
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
NPC1 O15118 1/20 0.45
KMT2A Q03164 1/20 0.45
GGPS1 O95749 1/20 0.44
NR1I2 O75469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13849636 0.91 POLB (0.62) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL15295402 0.88 ALDH1A1 (0.65) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL24675642 0.86 POLB (0.57) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL5245986 0.86 CYP4F2 (0.54) POLBALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL12970221 0.85 KDM4E (0.58) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL14724394 0.85 ALDH1A1 (0.57) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL59488 0.85 KDM4E (0.61) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL6002995 0.85 KDM4E (0.53) POLBALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL10334435 0.83 CYP4F2 (0.69) POLBALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL11050996 0.83 KDM4E (0.60) POLBALDH1A1KDM4ESMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115605452-B Polyhydroxy aromatic intermediate, preparation method thereof and application of polyhydroxy aromatic intermediate in polycondensate water reducer containing branched side chains 江苏苏博特新材料股份有限公司 2024-06-11 CN claimed
WO-2023082175-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN POLYCONDENSATE WATER REDUCER CONTAINING BRANCHED SIDE CHAIN 江苏苏博特新材料股份有限公司 2023-05-19 WO claimed
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BOTE NEW MATERIALS TAIZHOU CO., LTD. (CN) 2023-05-18 US claimed
CN-115605452-A Polyhydroxy aromatic intermediate, preparation method thereof and application thereof in polycondensate water reducing agent containing branched side chain 江苏苏博特新材料股份有限公司(CN) 2023-01-13 CN claimed
US-12528907-B2 Polyhydroxy aromatic intermediate, preparation thereof and use thereof in polycondensate water-reducer with branched side chains SOBUTE NEW MATERIALS CO., LTD. (CN) 2026-01-20 US disclosed
CN-118340754-B Compound for treating heart failure and related diseases and application thereof 源道医药(苏州)有限公司 2025-03-11 CN disclosed
CN-119490387-A Compounds for the treatment of pain-related diseases 源道医药(苏州)有限公司 2025-02-21 CN disclosed
CN-118340754-A Compound for treating heart failure and related diseases and application thereof 源道医药(苏州)有限公司 2024-07-16 CN disclosed
CN-115605452-B Polyhydroxy aromatic intermediate, preparation method thereof and application of polyhydroxy aromatic intermediate in polycondensate water reducer containing branched side chains 江苏苏博特新材料股份有限公司 2024-06-11 CN disclosed
CN-111465589-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-01-05 CN disclosed
WO-2023082175-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN POLYCONDENSATE WATER REDUCER CONTAINING BRANCHED SIDE CHAIN 江苏苏博特新材料股份有限公司 2023-05-19 WO disclosed
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BOTE NEW MATERIALS TAIZHOU CO., LTD. (CN) 2023-05-18 US disclosed
US-7524841-B2 4,4-disubstituted piperidine derivatives having CCR3 antagonism TEIJIN LIMITED (JP) 2009-04-28 US disclosed
US-7524841-B2 4,4-disubstituted piperidine derivatives having CCR3 antagonism TEIJIN LIMITED (JP) 2009-04-28 US disclosed
US-7517875-B2 Piperidine derivatives having CCR3 antagonism TEIJIN LIMITED (JP) 2009-04-14 US disclosed
US-7517875-B2 Piperidine derivatives having CCR3 antagonism TEIJIN LIMITED (JP) 2009-04-14 US disclosed
WO-2007042660-A2 SUBSTITUTED 1-AMINO-PHTHALZINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2007-04-19 WO disclosed
US-20070032525-A1 Piperidine derivatives having ccr3 antagonism TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) 2007-02-08 US disclosed
US-6476258-B1 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-05 US disclosed
EP-1067108-A2 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032525-A1 Piperidine derivatives having ccr3 antagonism CCR3, CCR1, CCR4 POLB 3628/4885ALDH1A1 451/4885KDM4E 3395/4885
US-12528907-B2 Polyhydroxy aromatic intermediate, preparation thereof and use thereof in polycondensate water-reducer with branched side chains IPMK, GRHPR, PIEZO1 POLB 241/4885ALDH1A1 4367/4885KDM4E 121/4885
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BICRA, GRHPR, SMARCC2 POLB 268/4885ALDH1A1 4140/4885KDM4E 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.