SCHEMBL5159788

SCHEMBL5159788

CCNS(=O)(=O)c1cc(S(N)(=O)=O)ccc1C

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
LMNA P02545 2/20 0.51
BRD4 O60885 1/20 0.49
BRD2 P25440 1/20 0.49
BRD3 Q15059 1/20 0.49
SFRP1 Q8N474 1/20 0.47
CYP2C9 P11712 1/20 0.45
KDM4E B2RXH2 2/20 0.45
VCAM1 P19320 1/20 0.42
CA2 P00918 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320070 0.80 BRD4 (0.51) ALDH1A1LMNABRD4BRD2BRD3
SCHEMBL17319218 0.80 SMN1; SMN2 (0.60) ALDH1A1LMNABRD4BRD2BRD3
SCHEMBL28904120 0.79 KMT2A (0.49) ALDH1A1CA2SMN1; SMN2
SCHEMBL1925948 0.79 CA2 (0.52) LMNABRD4BRD2BRD3CA2
P-Toluenesulfonamide SCHEMBL15517091 0.78 ALDH1A1 (0.82) ALDH1A1CYP2C9CA2
SCHEMBL27975322 0.78 CA2 (0.61) ALDH1A1BRD4CYP2C9VCAM1CA2
SCHEMBL6220009 0.78 CA2 (0.47) ALDH1A1LMNACA2HTT
SCHEMBL1685394 0.77 BRD4 (0.51) ALDH1A1LMNABRD4BRD2BRD3
SCHEMBL9320064 0.77 BRD4 (0.51) ALDH1A1LMNABRD4BRD2BRD3
SCHEMBL3950897 0.75 CA1 (0.48) ALDH1A1LMNACA2SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070179211-A1 Energy-curable intaglio printing SUN CHEMICAL CORPORATIN (US) 2007-08-02 US disclosed
EP-1751241-A1 ENERGY-CURABLE INTAGLIO PRINTING INKS Sun Chemical Corporation (US) 2007-02-14 EP disclosed
WO-2005097927-A1 ENERGY-CURABLE INTAGLIO PRINTING INKS SUN CHEMICAL CORPORATION (US) 2005-10-20 WO disclosed