SCHEMBL9320064

SCHEMBL9320064

CCNS(=O)(=O)c1cc([NH])ccc1C

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.51
BRD2 P25440 1/20 0.51
BRD3 Q15059 1/20 0.51
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.43
MEP1B Q16820 1/20 0.42
LMNA P02545 1/20 0.42
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
SFRP1 Q8N474 1/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17319218 0.82 SMN1; SMN2 (0.60) BRD4BRD2BRD3ALDH1A1SMN1; SMN2
SCHEMBL9320649 0.82 ALDH1A1 (0.52) BRD4BRD2BRD3ALDH1A1SMN1; SMN2
SCHEMBL9320638 0.81 GAA (0.49) ALDH1A1SMN1; SMN2LMNAGLAKDM4E
SCHEMBL9321505 0.80 LMNA (0.65) BRD4ALDH1A1SMN1; SMN2LMNATSHR
SCHEMBL9320621 0.80 CYP2D6 (0.44) BRD4BRD2BRD3ALDH1A1SMN1; SMN2
SCHEMBL1685394 0.79 BRD4 (0.51) BRD4BRD2BRD3ALDH1A1SMN1; SMN2
SCHEMBL9320070 0.79 BRD4 (0.51) BRD4BRD2BRD3ALDH1A1SMN1; SMN2
SCHEMBL5159788 0.77 ALDH1A1 (0.54) BRD4BRD2BRD3ALDH1A1SMN1; SMN2
SCHEMBL19285885 0.76 ALOX5AP (0.52) BRD4BRD2BRD3ALDH1A1HTT
SCHEMBL30194714 0.74 PKM (0.53) BRD4BRD2BRD3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372315-B1 Reactive dyes based on copper formazane BASF AG (DE) 1994-01-26 EP disclosed
US-5245020-A Reactive dyes with two or three nitrogen-containing haloheterocycles as reactive system BASF AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed
US-5149789-A Triazine dyes BASF AKTIENGESELLSCHAFT (DE) 1992-09-22 US disclosed
US-5041540-A For dyeing or printing hydroxyl- or nitrogen-containing substrates BASF AKTIENGESELLSCHAFT (DE) 1991-08-20 US disclosed
EP-0391264-A1 Reactive dyes with two or three halogen-N-heterocycles as reactive groups BASF Aktiengesellschaft (DE) 1990-10-10 EP disclosed
EP-0372315-A1 Reactive dyes based on copper formazane BASF Aktiengesellschaft (DE) 1990-06-13 EP disclosed