SCHEMBL5159977

SCHEMBL5159977

O=CCCCC(=O)C1CC(=O)OC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8345909 0.77 PRKCA (0.52) ALDH1A1TSHRPRKCA
SCHEMBL8990080 0.72
SCHEMBL510112 0.72
SCHEMBL13993783 0.69 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL2623083 0.69 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL476049 0.67 ALDH1A1 (0.32) ALDH1A1
SCHEMBL8764997 0.67 ALDH1A1 (0.32) ALDH1A1
SCHEMBL4419654 0.66
SCHEMBL575023 0.65 SMN1; SMN2 (0.32) ALDH1A1TSHR
SCHEMBL510221 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457464-A CD19 binding molecules and uses thereof 南京传奇生物科技有限公司 2023-07-18 CN disclosed
EP-0938497-B1 CONSTRAINED HELICAL PEPTIDES AND METHODS OF MAKING SAME GENENTECH INC (US) 2007-02-28 EP disclosed
EP-0938497-A1 CONSTRAINED HELICAL PEPTIDES AND METHODS OF MAKING SAME Genentech, Inc. (US) 1999-09-01 EP disclosed
WO-1998020036-A1 CONSTRAINED HELICAL PEPTIDES AND METHODS OF MAKING SAME GENENTECH, INC. (US) 1998-05-14 WO disclosed