Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359314 | 0.83 | HTR2B (0.42) | LMNATSHRACHESMN1; SMN2TDP1 | |
| SCHEMBL13059072 | 0.83 | ACHE (0.43) | LMNAHTTTSHRCYP2C9ACHE | |
| SCHEMBL5286553 | 0.83 | ACHE (0.43) | LMNAHTTTSHRCYP2C9ACHE | |
| SCHEMBL11691601 | 0.80 | CASP1 (0.45) | LMNAHTTTSHRSMN1; SMN2TDP1 | |
| SCHEMBL10359364 | 0.80 | NPSR1 (0.48) | LMNACYP2C9ACHESMN1; SMN2CYP1A2 | |
| SCHEMBL10358916 | 0.80 | NPSR1 (0.46) | LMNACYP2C9ACHESMN1; SMN2CYP1A2 | |
| SCHEMBL14394376 | 0.80 | TSHR (0.36) | LMNATSHRTDP1HTR2BGAA | |
| SCHEMBL18231221 | 0.79 | ACHE (0.40) | LMNAHTTTSHRCYP2C9ACHE | |
| SCHEMBL9774774 | 0.79 | TSHR (0.44) | LMNAHTTTSHRCYP2C9ACHE | |
| SCHEMBL7277166 | 0.77 | TDP1 (0.59) | LMNAHTTTSHRCYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111465589-B | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2024-01-05 | — | — | CN | disclosed |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | TEIJIN LIMITED (JP) | 2022-05-24 | — | — | US | disclosed |
| EP-3747856-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | Teijin Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | TEIJIN LIMITED (JP) | 2020-11-12 | — | — | US | disclosed |
| CN-111465589-A | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2020-07-28 | — | — | CN | disclosed |
| WO-2020085222-A1 | CRYSTAL OF COMPOUND HAVING FLUORENE SKELETON AND METHOD FOR PRODUCING SAME | 帝人株式会社 | 2020-04-30 | — | — | WO | disclosed |
| WO-2019151264-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | 帝人株式会社 | 2019-08-08 | — | — | WO | disclosed |
| CN-102388012-B | Method for producing fluorene derivative | TAOKA CHEMICAL Co.,Ltd. (JP) | 2014-10-15 | — | — | CN | disclosed |
| US-8841491-B2 | Method for producing fluorene derivative | TAOKA CHEMICAL CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| EP-2420485-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | Taoka Chemical Co., Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | TAOKA CHEMICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-0391942-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYACETIC ACID | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-10-17 | — | — | EP | disclosed |
| US-4935540-A | OXIDIZING ARYLOXYETHANOL IN PRESENCE OF PALLADIUM AND THALLIU M ON CARBON CATALYST, ACIDIFYING | EASTMAN CHEMICAL COMPANY | 1990-06-19 | — | — | US | disclosed |
| WO-1989003378-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYACETIC ACID | EASTMAN KODAK COMPANY (US) | 1989-04-20 | — | — | WO | disclosed |
| US-4804777-A | OXIDATION OF ARYLOXYETHANOL USING PALLADIUM, SILVER, CARBON CATALYST | EASTMAN KODAK COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0011793-B1 | PROCESS FOR PREPARING ARYLOXYACETIC ACIDS | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4238625-A | ACTIVATORS OF LEAD AND/OR BISMUTH AND/OR THEIR COMPOUNDS FOR OXIDATION WITH PLATINUM OR PALLADIUM CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0011793-A1 | Process for preparing aryloxyacetic acids | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | RFT1, AFF1, RER1 | LMNA 1995/4885HTT 2807/4885TSHR 2403/4885 |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | ADH1A, AFF2, AFF1 | LMNA 1363/4885HTT 2816/4885TSHR 1365/4885 |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | RFT1, AFF1, RER1 | LMNA 1995/4885HTT 2807/4885TSHR 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.