Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418202 | 0.90 | HRH3 (0.44) | HRH3TMPRSS15SCDALDH1A1 | |
| Hydrochloric Acid SCHEMBL5158987 | 0.89 | HRH3 (0.43) | HRH3TMPRSS15SCDALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5161930 | 0.89 | HRH3 (0.43) | HRH3TMPRSS15SCDALDH1A1GAA | |
| SCHEMBL5163240 | 0.87 | HRH3 (0.42) | HRH3TMPRSS15SCDALDH1A1 | |
| Hydrochloric Acid SCHEMBL5161121 | 0.85 | HRH3 (0.43) | HRH3TMPRSS15SCDALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5160760 | 0.85 | HRH3 (0.45) | HRH3TMPRSS15SCDALDH1A1 | |
| SCHEMBL5161507 | 0.84 | HRH3 (0.40) | HRH3TMPRSS15ALDH1A1GAAMEN1 | |
| Hydrochloric Acid SCHEMBL5160939 | 0.84 | HRH3 (0.39) | HRH3TMPRSS15ALDH1A1GAAMEN1 | |
| SCHEMBL5160259 | 0.81 | HRH3 (0.36) | HRH3TMPRSS15ALDH1A1GAAMEN1 | |
| SCHEMBL5163227 | 0.81 | PDE3B (0.47) | SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | HRH3 468/4885CNR2 2841/4885TMPRSS15 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.