Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5160939 | 0.99 | HRH3 (0.39) | HRH3TMPRSS15CHRM4ALDH1A1MEN1 | |
| SCHEMBL5418202 | 0.87 | HRH3 (0.44) | HRH3TMPRSS15ALDH1A1AOC3 | |
| Hydrochloric Acid SCHEMBL5161930 | 0.86 | HRH3 (0.43) | HRH3TMPRSS15ALDH1A1AOC3GAA | |
| Hydrochloric Acid SCHEMBL5158987 | 0.86 | HRH3 (0.43) | HRH3TMPRSS15ALDH1A1AOC3GAA | |
| SCHEMBL5160264 | 0.84 | HRH3 (0.46) | HRH3TMPRSS15ALDH1A1MEN1KMT2A | |
| SCHEMBL5163240 | 0.84 | HRH3 (0.42) | HRH3TMPRSS15ALDH1A1 | |
| SCHEMBL5163538 | 0.84 | OPRK1 (0.44) | HRH3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5160760 | 0.83 | HRH3 (0.45) | HRH3TMPRSS15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5161121 | 0.83 | HRH3 (0.43) | HRH3TMPRSS15ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5163218 | 0.83 | TMPRSS15 (0.37) | HRH3TMPRSS15ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | HRH3 468/4885TMPRSS15 1554/4885CHRM4 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.