Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 10/20 | 0.42 |
| ▸ | NOS3 | P29474 | 6/20 | 0.42 |
| ▸ | NOS2 | P35228 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158843 | 0.89 | NOS1 (0.43) | NOS1NOS3NOS2SLC6A4MPO | |
| SCHEMBL427400 | 0.79 | TAAR1 (0.43) | NOS1NOS3NOS2SLC6A4 | |
| SCHEMBL5161540 | 0.78 | NOS1 (0.46) | NOS1NOS3NOS2SLC6A4 | |
| SCHEMBL5161523 | 0.75 | ALDH1A1 (0.37) | NOS1NOS3NOS2 | |
| SCHEMBL5158731 | 0.74 | HCAR2 (0.32) | — | |
| SCHEMBL5160277 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL14875929 | 0.73 | NOS1 (0.40) | NOS1NOS3NOS2SLC6A4MPO | |
| SCHEMBL5190941 | 0.70 | PRKCI (0.54) | NOS1NOS3NOS2SLC6A4 | |
| SCHEMBL8590051 | 0.70 | SLC6A4 (0.43) | NOS1NOS3NOS2SLC6A4MPO | |
| SCHEMBL5158799 | 0.70 | ALDH1A1 (0.52) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | KRT18, DSP, CDC73 | NOS1 1779/4885NOS3 2100/4885NOS2 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.