Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192245 | 0.89 | PRKCI (0.58) | PRKCIACHEALDH1A1MAPTTDP1 | |
| SCHEMBL5192142 | 0.83 | PRKCI (0.70) | PRKCIACHEALDH1A1MAPTTDP1 | |
| SCHEMBL14875929 | 0.82 | NOS1 (0.40) | PRKCIACHESLC6A4NOS3NOS1 | |
| SCHEMBL427400 | 0.81 | TAAR1 (0.43) | ALDH1A1CYP3A4SLC6A4KMT2ANOS3 | |
| SCHEMBL309824 | 0.80 | PRKCI (0.59) | PRKCIACHEMAPTTDP1CYP3A4 | |
| SCHEMBL3338265 | 0.80 | PRKCI (0.69) | PRKCIACHEALDH1A1MAPTTDP1 | |
| SCHEMBL29834174 | 0.80 | PRKCI (0.69) | PRKCIACHEALDH1A1MAPTTDP1 | |
| SCHEMBL21214846 | 0.79 | PRKCI (0.59) | PRKCIACHEALDH1A1MAPTTDP1 | |
| SCHEMBL8590051 | 0.79 | SLC6A4 (0.43) | PRKCISLC6A4NOS3NOS1NOS2 | |
| SCHEMBL3579492 | 0.79 | PRKCI (0.58) | PRKCIACHEALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361851-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2007-02-21 | — | — | EP | disclosed |
| US-7070630-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1361851-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-6750339-B2 | SUCH AS 4-AMINO-2-(2-DIMETHYLAMINO-ETHYL)-PHENOL; USEFUL IN PLACE OF P-AMINOPHENOL | THE PROCTER AND GAMBLE COMPANY | 2004-06-15 | — | — | US | disclosed |
| EP-1361851-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G-Clairol, Inc. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-17 | — | — | US | disclosed |
| WO-2002058653-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | PRKCI 3484/4885ACHE 4672/4885ALDH1A1 70/4885 |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | PRKCI 3484/4885ACHE 4672/4885ALDH1A1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.